Protein fragment reconstruction using various modeling techniques

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Protein fragment reconstruction using various modeling techniques

Recently developed reduced models of proteins with knowledge-based force fields have been applied to a specific case of comparative modeling. From twenty high resolution protein structures of various structural classes, significant fragments of their chains have been removed and treated as unknown. The remaining portions of the structures were treated as fixed - i.e., as templates with an exact...

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ژورنال

عنوان ژورنال: Journal of Computer-Aided Molecular Design

سال: 2003

ISSN: 0920-654X

DOI: 10.1023/b:jcam.0000017486.83645.a0